A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential ...

Cryo-electron tomography has revealed how flaviviruses reorganise infected cells to enable replication and maturation with implications for future tick-borne encephalitis treatmentsResearchers at ...

Tick-borne encephalitis virus, known as TBEV, hijacks the internal membrane machinery of host cells to build hidden factories ...

Discovery reshapes understanding of how tumor cells repair broken DNA, pointing toward more precise cancer therapies.

Researchers at The University of Texas MD Anderson Cancer Center have identified an epigenetic target for replication stress, ...

Prior to cell division, chromosomes are seemingly a jumbled mess. During cell division, parent cell chromosomes and their duplicates sort themselves out by condensing, becoming thousands of times more ...

For almost 60 years, scientists have tried to understand why DNA doesn’t replicate wildly and uncontrollably every time a cell divides – which they need to do constantly. Without this process, we ...

“Our lab is generally interested in discovering and characterizing previously unknown or poorly understood factors that are essential for genome maintenance. This is particularly important in the ...

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

Researchers discovered a kinase-driven phosphorylation switch that activates DNA packaging machinery, aligning nucleosomes at ...