The energy invested in animal reproduction is as much as 10 times greater than previously estimated when the metabolic load of bearing and caring for offspring is accounted for, according to a new ...

Animal models from the Jackson Laboratory are available that reflect the genetic diversity of human populations. Taking genetic diversity into account is particularly important in basic research or ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

Too often, preclinical successes are followed by clinical failures. And all clinical failures hurt. Perhaps the most painful failures occur in trials that require large patient populations and long ...

This chapter examines how well specific animal models against biothreats of interest to the Transformational Medical Technologies (TMT) reflect various aspects of the human diseases for which medical ...